Oxidative Stress Pathways
Oxidative stress occurs when there is an imbalance between the production
of reactive oxygen species (ROS) and the body’s ability to neutralize
them.This imbalance can lead to damage to cells, proteins, and DNA.
Sources of Oxidative Stress
Pathways of Oxidative Stress
Oxidative stress can activate several signaling pathways that lead to cellular
damage and disease. Some key pathways include
Consequences of Oxidative Stress
Oxidative stress can contribute to a wide range of diseases, including
Cardiovascular disease, Cancer, Neurodegenerative diseases (e.g.,
Alzheimer’s, Parkinson’s), Diabetes, Insulin resistance, and Aging.
Antioxidant Defense Mechanisms
The body has several antioxidant defense mechanisms to counteract
oxidative stress. These include